This issue No. 3 (26) of “The Art of Eurasia” Journal is dedicated to avant-garde trends in Russian art in the second half of the 20th century. Sometimes they are called the avant-garde of the second wave, considering of futuristic art forms that arose at the turn of the 19th – 20th centuries as the first wave. The issue includes research presented at the conference “The Second Wave of Russian Avant-garde: Regional Versions” was interesting for us, which was held in Ekaterinburg in 2021 on the basis of the Department of art history and museum studies of the Ural Federal University. The trend of the avant-garde was quite large-scale and manifested itself not only in the capital centres, but also in almost all regions. The articles published here describe the avant-garde search in art from Odessa to Vladivostok and from the beginning of the 20th century to the present day. Thus, the question of the randomness and episodic nature of this phenomenon disappears, and the research focuses on its systematic study, analysis of the artistic and expressive form, deep ideological and philosophical content, and high humanistic and spiritual structure of works.